...It has been stated, as the result of fullresearch, that one wild pigeon, in whose crop over 7000 weedseeds were found, was as efficacious in destroying weeds as twofarm laborers... 
John Albert Leach 「An Australian Bird Book」
...For cauterizing thewound, fuming nitric acid, the hot iron, and 10 per cent solution of zincchlorid are the most efficacious...
U.S. Department of Agriculture 「Special Report on Diseases of Cattle」
...Can it be that my hypnotic tricks areless efficacious with small birds than with large ones? To judge bythe Pigeon, this may well be so...
Jean Henri Fabre Alexander Teixeira de Mattos 「The Glow-Worm and Other Beetles」
...It is an odious, but a supremely efficacious method...
J. Henri Fabre Alexander Teixeira de Mattos 「The Mason-bees」
...A splendid tool, as you say, for gathering the viscous pellet; quite as efficacious in its kind of work as is the rake of the toothed mandibles for gathering cotton...
J. Henri Fabre 「Bramble-bees and Others」
...They will not refuse even spirits or wine,administered in the same manner; but it is very questionable if theseare equally efficacious...
R. Lee 「Anecdotes of the Habits and Instinct of Animals」
...The unguent isbelieved to be very efficacious, but during its application thewoman's feet may not come into contact with the ground, or all thebenefit of the nostrum would be lost...
Sir James George Frazer 「Balder The Beautiful, Vol. I.」
...I am confident that this is the only efficacious method of makinga progress in the arts; and that he who sets out with doubting willfind life finished before he becomes master of the rudiments...
Joshua Reynolds 「Seven Discourses on Art」
...Someone, criminal or otherwise, against whom our shotgun would be efficacious...
Raymond King Cummings 「The White Invaders」
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